Eif2ak3 CLIA Kit for Rat(Rattus norvegicus) | EIAab.comEif2ak3 CLIA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Eif2ak3(Gene name) > Rat

Eif2ak3 (Gene name),

Eukaryotic translation initiation factor 2-alpha kinase 3 (Protein name ), E2AK3_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Eif2ak3(Pek;Perk);

Protein name:

Eukaryotic translation initiation factor 2-alpha kinase 3;

Alternative:

Pancreatic eIF2-alpha kinase;PRKR-like endoplasmic reticulum kinase;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with DNAJC3 (By similarity). Forms dimers with HSPA5/BIP in resting cells. Oligomerizes in ER-stressed cells.

Function:

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1108

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1108:

TFSPLPGN

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q9Z1Z1

UniGene:

Rn.24897

KEGG:

rno:29702

Pfam:

PF00069

STRING:

10116.ENSRNOP00000008451

Uniprot:

Q9Z1Z1

FOR

ELISA Kit for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

E11434h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

E11434m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

E11434r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

U11434h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

U11434r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

U11434m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Cat.:

P11434Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Monoclonal Antibody for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

Protein for Rat Eukaryotic translation initiation factor 2-alpha kinase 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control."
Shi Y. , Vattem K.M. , Sood R. , An J. , Liang J. , Stramm L.E. , Wek R.C.
Mol. Cell. Biol.18:7499-7509(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
tissue: Pancreatic islet.
2.

"Characterization of a mutant pancreatic eIF-2alpha kinase, PEK, and co-localization with somatostatin in islet delta cells."
Shi Y. , An J. , Liang J. , Hayes S.E. , Sandusky G.E. , Stramm L.E. , Yang N.N.
J. Biol. Chem.274:5723-5730(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF LYS-614
3.

"Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response."
Bertolotti A. , Zhang Y. , Hendershot L.M. , Harding H.P. , Ron D.
Nat. Cell Biol.2:326-332(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT

Product Feedback Wall

* Email:
*Comments: